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KMID : 1123920100240010102
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Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 1 p.102 ~ p.110
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Effects of Mahwangimun-tang in Cholesterol Diet and Triton WR-1339 -induced Hyperlipidemic Rats
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Kim Hak-Joon
Kim Jeung-Beum
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Abstract
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This study was designed to investigate the hyperlipidemia-healing effect of aqueous extract from Mahwangimun-tang(麻黃二門湯) and it was performed on the hyperlipidemia of rats induced by high cholesterol diet and Triton WR-1339. We prepared two types of hyperlipidemia model in rats induced by high cholesterol diet and Triton WR-1339. The amount of total cholesterol, HDL-cholesterol, LDL -cholesterol, triglyceride, phospholipid, free fatty acid, the activity of superoxide dismutase and glutathione were measured. The aqueous extract from Mahwangimun-tang showed significant decreasing effects on total cholesterol, LDL- cholesterol, triglyceride in the both model. And it showed significant increasing effects on HDL-cholesterol, the activity of SOD in both model. These results suggest that aqueous extract from Mahwangimun-tang has healing efficacy on hyperlipidemia induced by high cholesterol diet and Triton WR-1339.
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KEYWORD
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Mahwangimun-tang(麻黃二門湯), hyperlipidemia, total cholesterol, triglyceride, HDL-cholesterol, LDLcholesterol
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